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本書是《哈里森內科學（第19版）》的減縮版口袋書，內容涵蓋病因與流行病學、臨床相關病理生理學、症狀與體征、診斷與鑒別診斷、體格檢查與實驗室檢查、診療要點、實用指南等，著重呈現了醫學實踐中常見疾病的臨床表現、診斷和治療要點，寫作特點突出。本書以全彩、簡潔實用、方便攜帶為特色，為臨床診療、查房提供速查資料。
Dennis L.Kasper博士是威廉埃勒裡強尼的醫學教授；任哈佛醫學院微生物學與免疫生物學系免疫分部微生物學和免疫生物學教授；同時在麻塞諸塞州的波士頓布萊根婦女醫院任職。
Contributors................................................xv
Preface...................................................xvii
Acknowledgments..........................................xix
SECTION 1 CARE OF THE HOSPITALIZED PATIENT
1 Electrolytes/Acid-Base Balance....................................................1
2 Diagnostic Imaging in Internal Medicine..................................23
3 Procedures Commonly Performed by Internists......................26
4 Principles of Critical Care Medicine...........................................31
5 Pain and Its Management...........................................................35
6 Assessment of Nutritional Status...............................................40
7 Enteral and Parenteral Nutrition...............................................43
8 Transfusion and Pheresis Therapy.............................................46
9 Palliative and End-of-Life Care...................................................48
SECTION 2 MEDICAL EMERGENCIES
10 Cardiovascular Collapse and Sudden Death.............................57
11 Shock............................................................................................61
12 Sepsis and Septic Shock..............................................................65
13 Acute Pulmonary Edema............................................................69
14 Acute Respiratory Distress Syndrome.......................................71
15 Respiratory Failure......................................................................73
16 Confusion, Stupor, and Coma....................................................76
17 Stroke...........................................................................................82
18 Subarachnoid Hemorrhage........................................................91
19 Increased Intracranial Pressure and Head Trauma..................93
20 Spinal Cord Compression...........................................................98
21 Hypoxic-Ischemic Encephalopathy..........................................100
22 Status Epilepticus......................................................................101
23 Diabetic Ketoacidosis and Hyperosmolar Coma....................104
24 Hypoglycemia............................................................................107
25 Oncologic Emergencies.............................................................109
26 Anaphylaxis...............................................................................114
27 Bites, Venoms, Stings, and Marine Poisonings.......................115
SECTION 3 COMMON PATIENT PRESENTATIONS
28 Fever, Hyperthermia, and Rash................................................127
29 Generalized Fatigue..................................................................131
30 Weight Loss................................................................................135
31 Chest Pain..................................................................................137
32 Palpitations................................................................................141
33 Dyspnea......................................................................................142
34 Cyanosis.....................................................................................145
35 Cough and Hemoptysis.............................................................146
36 Edema.........................................................................................150
37 Abdominal Pain.........................................................................154
38 Nausea, Vomiting, and Indigestion.........................................158
39 Dysphagia..................................................................................162
40 Diarrhea, Malabsorption, and Constipation...........................167
41 Gastrointestinal Bleeding.........................................................174
42 Jaundice and Evaluation of Liver Function.............................178
43 Ascites........................................................................................187
44 Lymphadenopathy and Splenomegaly...................................189
45 Anemia and Polycythemia........................................................194
46 Azotemia and Urinary Abnormalities......................................197
47 Pain and Swelling of Joints.......................................................203
48 Back and Neck Pain...................................................................207
49 Headache...................................................................................215
50 Syncope......................................................................................222
51 Dizziness and Vertigo...............................................................226
52 Acute Visual Loss and Double Vision......................................229
53 Weakness and Paralysis............................................................233
54 Tremor and Movement Disorders............................................236
55 Aphasia.......................................................................................239
56 Sleep Disorders..........................................................................241
57 Dysuria and Bladder Pain.........................................................245
SECTION 4 OTOLARYNGOLOGY
58 Sore Throat, Earache, and Upper
Respiratory Symptoms.............................................................247
SECTION 5 DERMATOLOGY
59 General Examination of the Skin.............................................255
60 Common Skin Conditions.........................................................258
SECTION 6 HEMATOLOGY AND ONCOLOGY
61 Examination of Blood Smears and Bone Marrow...................265
62 Red Blood Cell Disorders..........................................................267
63 Leukocytosis and Leukopenia..................................................274
64 Bleeding and Thrombotic Disorders.......................................277
65 Myeloid Leukemias, Myelodysplasia, and
Myeloproliferative Syndromes................................................283
66 Lymphoid Malignancies............................................................293
67 Skin Cancer................................................................................305
68 Head and Neck Cancer..............................................................308
69 Lung Cancer...............................................................................310
70 Breast Cancer.............................................................................316
71 Tumors of the Gastrointestinal Tract......................................321
72 Genitourinary Tract Cancer......................................................333
73 Gynecologic Cancer...................................................................338
74 Prostate Hyperplasia and Carcinoma......................................342
75 Cancer of Unknown Primary Site.............................................345
76 Paraneoplastic Endocrine Syndromes.....................................348
77 Neurologic Paraneoplastic Syndromes...................................352
SECTION 7 INFECTIOUS DISEASES
78 Infections Acquired in Health Care Facilities..........................357
79 Infections in the Immunocompromised Host.........................362
80 Infective Endocarditis...............................................................372
81 Intraabdominal Infections........................................................382
82 Infectious Diarrheas..................................................................386
83 Sexually Transmitted and Reproductive Tract Infections.....399
84 Infections of the Skin, Soft Tissues, Joints, and Bones..........415
85 Pneumococcal Infections..........................................................422
86 Staphylococcal Infections.........................................................425
87 Streptococcal/Enterococcal Infections, Diphtheria,
and Infections Caused by Other Corynebacteria
and Related Species..................................................................434
88 Meningococcal and Listerial Infections...................................443
89 Infections Caused by Haemophilus, Bordetella,
Moraxella, and HACEK Group Organisms...............................448
90 Diseases Caused by Gram-Negative Enteric
Bacteria and Pseudomonas.......................................................453
91 Infections Caused by Miscellaneous
Gram-Negative Bacilli...............................................................462
92 Anaerobic Infections.................................................................469
93 Nocardiosis, Actinomycosis, and Whipple’s Disease.............477
94 Tuberculosis and Other Mycobacterial Infections.................482
95 Lyme Disease and Other Nonsyphilitic
Spirochetal Infections...............................................................494
96 Rickettsial Diseases...................................................................500
97 Mycoplasma pneumoniae, Legionella Species, and
Chlamydia pneumoniae.............................................................510
98 Chlamydia trachomatis and C. psittaci.....................................514
99 Herpesvirus Infections..............................................................516
100 Cytomegalovirus and Epstein-Barr Virus Infections..............525
101 Influenza and Other Viral Respiratory Diseases.....................530
102 Rubeola, Rubella, Mumps, and Parvovirus Infections...........538
103 Enteroviral Infections................................................................543
104 Insect- and Animal-Borne Viral Infections..............................546
105 HIV Infection and AIDS.............................................................554
106 Fungal Infections.......................................................................568
107 Pneumocystis Infections............................................................583
108 Protozoal Infections..................................................................586
109 Helminthic Infections and Ectoparasite
Infestations................................................................................599
SECTION 8 CARDIOLOGY
110 Physical Examination of the Heart...........................................613
111 Electrocardiography.................................................................618
112 Noninvasive Examination of the Heart...................................622
113 Congenital Heart Disease in the Adult....................................627
114 Valvular Heart Disease..............................................................632
115 Cardiomyopathies and Myocarditis........................................639
116 Pericardial Disease....................................................................644
117 Hypertension.............................................................................649
118 Metabolic Syndrome.................................................................656
119 ST-Segment Elevation Myocardial
Infarction....................................................................................658
120 Unstable Angina and Non-ST-Elevation
Myocardial Infarction................................................................668
121 Chronic Stable Angina..............................................................672
122 Bradyarrhythmias.....................................................................677
123 Tachyarrhythmias.....................................................................679
124 Heart Failure and Cor Pulmonale.............................................687
125 Diseases of the Aorta................................................................693
126 Peripheral Vascular Disease.....................................................696
127 Pulmonary Hypertension..........................................................699
SECTION 9 PULMONOLOGY
128 Respiratory Function and Pulmonary
Diagnostic Procedures..............................................................705
129 Asthma.......................................................................................711
130 Environmental Lung Diseases..................................................715
131 Chronic Obstructive Pulmonary Disease.................................718
132 Pneumonia, Bronchiectasis, and Lung Abscess......................722
133 Pulmonary Thromboembolism and Deep-Vein
Thrombosis................................................................................730
134 Interstitial Lung Disease...........................................................734
135 Diseases of the Pleura and Mediastinum................................740
136 Disorders of Ventilation............................................................744
137 Sleep Apnea...............................................................................745
SECTION 10 NEPHROLOGY
138 Acute Renal Failure...................................................................747
139 Chronic Kidney Disease and Uremia........................................752
140 Dialysis.......................................................................................754
141 Renal Transplantation..............................................................756
142 Glomerular Diseases.................................................................759
143 Renal Tubular Disease...............................................................769
144 Urinary Tract Infections and Interstitial Cystitis....................775
145 Nephrolithiasis..........................................................................779
146 Urinary Tract Obstruction.........................................................782
SECTION 11 GASTROENTEROLOGY
147 Peptic Ulcer and Related Disorders.........................................785
148 Inflammatory Bowel Diseases..................................................790
149 Colonic and Anorectal Diseases...............................................794
150 Cholelithiasis, Cholecystitis, and Cholangitis.........................799
151 Pancreatitis................................................................................804
152 Acute Hepatitis..........................................................................809
153 Chronic Hepatitis.......................................................................816
154 Cirrhosis and Alcoholic Liver Disease......................................826
155 Portal Hypertension..................................................................831
SECTION 12 ALLERGY, CLINICAL IMMUNOLOGY, AND RHEUMATOLOGY
156 Diseases of Immediate-Type Hypersensitivity.......................835
157 Primary Immune Deficiency Diseases.....................................840
158 Systemic Lupus Erythematosus, Rheumatoid Arthritis,
and Other Connective Tissue Diseases....................................843
159 Vasculitis....................................................................................850
160 Ankylosing Spondylitis.............................................................854
161 Psoriatic Arthritis.......................................................................857
162 Reactive Arthritis.......................................................................859
163 Osteoarthritis.............................................................................861
164 Gout, Pseudogout, and Related Diseases...............................863
165 Other Musculoskeletal Disorders.............................................867
166 Sarcoidosis.................................................................................870
167 Amyloidosis...............................................................................873
SECTION 13 ENDOCRINOLOGY AND METABOLISM
168 Disorders of the Anterior Pituitary and Hypothalamus.........877
169 Diabetes Insipidus and Syndrome of Inappropriate
Antidiuretic Hormone...............................................................883
170 Thyroid Gland Disorders...........................................................886
171 Adrenal Gland Disorders..........................................................895
172 Obesity.......................................................................................901
173 Diabetes Mellitus.......................................................................904
174 Disorders of the Male Reproductive System...........................912
175 Disorders of the Female Reproductive System......................917
176 Hypercalcemia and Hypocalcemia...........................................924
177 Osteoporosis and Osteomalacia..............................................931
178 Hypercholesterolemia and Hypertriglyceridemia..................936
179 Hemochromatosis, Porphyrias, and Wilson’s Disease...........942
SECTION 14 NEUROLOGY
180 The Neurologic Examination....................................................947
181 Seizures and Epilepsy...............................................................956
182 Dementia....................................................................................968
183 Parkinson’s Disease...................................................................976
184 Ataxic Disorders........................................................................981
185 ALS and Other Motor Neuron Diseases...................................984
