內容簡介
Written in response to reader requests for a short, “to the point” text that clearly summarizes the most important chemical elements of therapeutically relevant drug classes, Essentials of Foye's Principles of Medicinal Chemistry is a concise, quick-reference source of reliable information in the field. Derived from the highly regarded Foye's Principles of Medicinal Chemistry, this focused text provides an essential understanding of drug action and demonstrates its practical application to today’s pharmacy practice.
• Highlights the “take home” chemical points of every chapter in the parent text, and uses an easy-to-read, bulleted format to convey essential concepts.
• Covers mechanism of action (MOA), structure-activity relationships (SAR), physicochemical and pharmacokinetic properties, metabolism, and clinical applications in all chapters.
• Uses numerous figures and tables to illustrate key concepts and make reference quick and easy.
• Summarizes additional information such as adverse effects, drug-drug or drug-food interactions, chemical points of interest, and unique aspects of clinical use in side boxes or Chemical Note side bars.
• Concludes each chapter with a section emphasizing the clinical relevance of chapter content, as well as review questions for self-assessment.
• Written by the same international team of renowned researchers and academicians as Foye’s Principles of Medicinal Chemistry
Now with the print edition, enjoy the bundled interactive eBook edition, which can be downloaded to your tablet and smartphone or accessed online and includes features like:
• Complete content with enhanced navigation
Powerful search tools and smart navigation cross-links that pull results from content in the book, your notes, and even the web
• Cross-linked pages, references, and more for easy navigation
• Highlighting tool for easier reference of key content throughout the text
• Ability to take and share notes with friends and colleagues
• Quick reference tabbing to save your favorite content for future use
作者介紹
作者簡介
Thomas L. Lemke PhD
Associate Dean for Professional Programs and Professor of Medicinal Chemistry, University of Houston, Houston, TX
S. William Zito PhD
College of Pharmacy and Allied Health Professions, St. John's University, Jamaica, NY
Victoria, PhD F. Roche PhD
Senior Associate Dean, School of Pharmacy and Health Professions, Creighton University, Omaha, NE
David A. Williams PhD
Emeritus Professor of Chemistry, Massachusetts College of Pharmacy and Health Sciences, Boston, MA
目錄
1. Essentials of Essentials
2. Introduction to Medicinal Chemistry: Drug Receptors and General Drug Metabolism
3. Cholinergic Agents
4. Adrenergic Agents
5. Drugs Used to Treat Neuromuscular Disorders
6. respiratory Agents
7. Antipsychotic and Anxiolytic Drugs
8. Sedative-Hypnotics
9. Anesthetic Agents: General and Local Anesthetics
10. Antiseizure Agents
11. Antidepressants
12. Opioid Analgesics and Antagonists
13. Cardiovascular Agents
14. Agents Affecting the Renin-Angiotensin Pathway
15. Antihyperlipidemics
16. Anticoagulant, Antiplatelet, and Fibrinolysis Agents
17. Insulin and Drugs Used to Treat Diabetes
18. Steroids: Adrenocorticoids, Androgens, Estrogens, and related Nonsteroidal Compounds
19. Thyroid Function and Thyroid Drugs
20. Calcium Homeostasis
21. Nonsteroidal Anti-Inflammatory Drugs
22. Antihistamines and Related Antiallergic and Antiulcer Agents
23. Antimicrobial Agents
24. Antifungal Agents
25. Antiparasitic Drugs
26. Cancer Chemotherapy
27. Chemotherapy: Antiviral and Antiretroviral Agents
28. Obesity and Nutrition
Abbreviations
Answers to Review Questions
Subject Index
Drug Index
